Daicel 81511 CHIRALPAK ® IB-3 Polysaccharide Derivatives Solvent-Rich Chiral Guard Cartridges (Pack of 3), 4mm, 10mm, 3µm
Silica gel is covalently bonded to cellulose-tris (3,5-dimethylphenylcarbamate)
IB solvent-resistant chiral column, silica gel surface covalently bonded with cellulose-tris (3,5-dimethylphenylcarbamate).
Solvents use unrestricted, wide dissolution conditions, any solvent can be used as a mobile solvent, dissolved samples, chiral column regeneration.
Solvents that can be used, for example:
Positive phase: n-Hexane, IPA, EtOH
Special mobile phase: Ethyl acetate, CH 3 Cl, THF, MTBE
Reverse phase: H 2 O, IPA, MeOH
Immobilized Polysaccharide Columns
Daicel immobilized columns exhibit greatly enhanced robustness and remarkable stability. These innovative products allow chromatographers to employ essentially any organic solvent as mobile phase to develop methods for the most challenging separations. The immobilized columns are used for applications ranging from analytical method development to large-scale enantiomer resolutions.
Driven by the need for increased productivity in the lab, Daicel Corporation has introduced the first sub-2 µm immobilized chiral columns, CHIRALPAK IA-U, CHIRALPAK IB-U, CHIRALPAK IC-U and CHIRALPAK IG-U. The ultrafast separations provided by sub-2 µm columns speed-up initial drug discovery and enable rapid high-throughput screening and method development. These columns are designed to be used with Ultra-High Performance Liquid Chromatography (UHPLC) systems to achieve ultrafast and high-resolution of enantiomers.
Parameters
| Filler particle size | CHIRALPAK ® IB-3: 3μm CHIRALPAK ® IB: 5μm CHIRALPAK ® IB-U: 1.6 μm |
|---|---|
| pressure | In order to extend the life of the chiral column, CHIRALPAK ® IB-3/CHIRALPAK ® IB recommends maintaining a pressure below 30 MPa. CHIRALPAK ® IB-U recommends maintaining a pressure below 70 MPa. |
| pH value | pH 2.0~9.0 |
| temperature | 0~40°C |
| Storage solvent | CHIRALPAK ® IB-3: n-Hexane/2-Propanol = 90/10 (v/v) CHIRALPAK ® IB: n-Hexane / 2-Propanol solvent mixture (95/5) CHIRALPAK ® IB-U: n-Hexane/2-Propanol solvent mixture= 90/10 (v/v) |