Daicel 80U83 CHIRALPAK ® IA-U Analytical HPLC Chiral Column - Polysaccharide Derivatives Solvent-Rich Chiral Column, 3.0mm, 100mm, 1.6µm
The surface of silica was covalently bound with amylose - tris (3,5-dimethylphenylcarbamate)
IA solvent-resistant chiral column, the amylose-tris (3,5-dimethylphenylcarbamate) covalently bonded to the surface of the silica gel.
Unrestricted use of solvents, a wide range of dissolution conditions, the use of any miscible solvent as a mobile phase, dissolved samples, chiral column regeneration.
Solvents that can be used, for example:
Positive phase: n-Hexane, IPA, EtOH
Special mobile phase: Ethyl acetate, CH 3 Cl, THF, MTBE
Reverse phase: H 2 O, IPA, MeOH
Immobilized Polysaccharide Columns
Daicel immobilized columns exhibit greatly enhanced robustness and remarkable stability. These innovative products allow chromatographers to employ essentially any organic solvent as mobile phase to develop methods for the most challenging separations. The immobilized columns are used for applications ranging from analytical method development to large-scale enantiomer resolutions.
Driven by the need for increased productivity in the lab, Daicel Corporation has introduced the first sub-2 µm immobilized chiral columns, CHIRALPAK IA-U, CHIRALPAK IB-U, CHIRALPAK IC-U and CHIRALPAK IG-U. The ultrafast separations provided by sub-2 µm columns speed-up initial drug discovery and enable rapid high-throughput screening and method development. These columns are designed to be used with Ultra-High Performance Liquid Chromatography (UHPLC) systems to achieve ultrafast and high-resolution of enantiomers.
|Filler particle size||CHIRALPAK ® IA-3: 3μm|
CHIRALPAK ® IA: 5μm
CHIRALPAK ® IA-U: Sub-2 μm
|pressure||To extend the life of the chiral column, CHIRALPAK ® IA-3 / CHIRALPAK ® IA recommends maintaining the pressure below 30 MPa.|
CHIRALPAK ® IA-U recommends keeping the pressure below 70MPa
|pH value||pH 2.0 ~ 9.0|
|temperature||0 ~ 40 ℃|
|Save the solvent||CHIRALPAK ® IA-3: n-Hexane / 2-Propanol = 90/10 (v / v)|
CHIRALPAK ® IA: n-Hexane / Ethanol = 90/10 (v / v)
CHIRALPAK ® IA-U: n-Hexane / 2-Propanol solvent mixture = 90/10 (v / v)
For column storage, remove the acidic or basic additives by flushing the column with the same mobile phase without the additive. Columns can be stored with the additive-free mobile phases. Operating these columns in accordance with the guidelines outlined here will result in a long column life
Country of OriginJapan
- Chromatography HPLC or GC
Particle size (µm)1.6
Internal Diameter (mm)3
Temperature range (°C)0 ~ 40 ℃
pH Range2.0 to 9.0
Packing PhaseCHIRALPAK ® IA-3