The Disposable Tip Hand Probe utilizes Hamilton's unique, environmentally-friendly ClickSure^® tips that have been validated for superior liquid handling. When ClickSure tips are placed onto the probe, the O-ring on the probe compresses into the tip groove. This design only requires a low insertion force to successfully load a tip, resulting in a more ergonomic experience for the user and enabling long-term use with minimal energy exerted. The probe accepts two ClickSure tips, 50 µL and 1 mL, which cover the entire pipetting volume range from 0.5 – 1000 µL.