CERI 752453 L-column2 C8 Octyl Cartridge Guard Column (Pack of 3), 0.3mm x 5mm, 5μm Particle Size

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Particle size3 μm, 5 μm
Pore diameter12 nm
Specific surface area340 m 2 / g
Carbon contentTen%
Modifying groupC8 (Octyl)
End capping methodAdvanced end capping
USP categoryL7
Operating pH rangepH 2 to 7.5

L-column2 C8 is a next-generation high-performance octyl-based column that surpasses L-column C8 by minimizing the influence of residual silanol groups by advanced end capping method . Of course it is a durable and easy to use column that peaks are detected sharply. Ideal for shortening the analysis time of hydrophobic substances and saving solvent accordingly.

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The trap column can be used to efficiently desalt and concentrate the target components with a column switching system.
The cartridge is mounted on the holder. Cartridges can be easily replaced 

Characteristics of C8 column

Short analysis time 

Generally, C8 column has lower retention compared to ODS column under the same analysis conditions, so elution time is faster. Hydrophobic substances can reduce analysis time and reduce solvent consumption. Fig. 1 is an example comparing fat-soluble vitamins under the same conditions. Vitamin K is highly hydrophobic and takes a long time to analyze in ODS, but L-column2 C8takes about 1/4 of the analysis time.

Separation pattern different from ODS column 

Since C8 column and ODS column may give different separation patterns, even if separation is impossible with ODS column, separation improvement may be possible with C8 column. Fig. 2 is a chromatogram comparing antidepressants under the same analytical conditions. The separation of desipramine and paroxetine has been greatly improved.

    • SKU
  • Manufacturer
    Chemicals Evaluation and Research Institute (CERI)
  • Chromatography HPLC or GC
    • Particle size (µm)
    • Internal Diameter (mm)
    • Length (mm)
    • pH Range
    • Packing Phase
      L-column2 C8